Testosterone therapy: Potential benefits and risks as you age

Testosterone Cypionate Injections

Testosterone belongs to a class of drugs known as androgens. It works by affecting many body systems so foods that boost testosterone and lower estrogen the body can develop and function normally. In some studies a decline in diastolic blood pressure has been observed, after 3–9 months (22, 35, 41, 44) and in some studies in systolic blood pressure also (35, 44). A decrease in the resting heart rate occurred after 40–44 weeks (44). A decrease in arterial stiffness measured as pulse wave velocity was measurable after 48 h (58) and in large artery compliance after 3 months (58). Several studies have been conducted in men with heart disease. In men with chronic stable angina pectoris the increase in time to 1 mm ST segment depression was noticeable after 14 weeks (59).

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly. The first transdermal patches found to be efficacious were scrotal patches in the 1980s (21).

Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions. Testosterone injection may control your symptoms but will not cure your condition. Your doctor may adjust your dose of testosterone depending on the amount of testosterone in your blood during your treatment and your reaction to the medication.

Enanthate is suspended in sesame oil while cypionate is suspended in cottonseed oil. Cypionate has a slightly slower release and longer active life, meaning it can be dosed every two weeks. Between the two, there is a difference in cost; cypionate is typically more relatively affordable. Testosterone cypionate first appeared on the U.S. prescription drug market during the early 1950s, as Depo-Testosterone by Upjohn, now Pharmacia & Upjohn. Due to testosterone cypionate’s vast similarity to the earlier released and slightly longer testosterone enanthate, it has received only limited global availability and is often identified as an American medication. Adherence rates differed from 7 to 12 months, with only 8.2% of those receiving testosterone cypionate continuing treatment at 12 months compared with 41.9% for testosterone undecanoate. Do not let anyone else use your testosterone enanthate injection (Xyosted).

Additionally, some of these medications are available in low-cost generic formulations. Disadvantages generally include less of a rise in testosterone levels compared to testosterone-containing therapies. Some of these medications are used off-label to increase testosterone. Cylindrical pellets that are about the size of a grain of rice.

It is recommended to check a testosterone level between 4 to 12 weeks after therapy initiation prior to the morning dose (14). About 80% of subjects maintained a Cavg above the lower normal limit at week 12 the majority (80%) of a 24-hour period (16). However, deprivation of testosterone and the time-dependent effects thereof might be totally different from the onset of testosterone action in testosterone treatment, even in the same parameter. Therefore, it was decided to restrict this paper to aspects of testosterone treatment. In hypogonadal men treated with testosterone, levels of PSA rise usually up to levels of eugonadal men (84). A rise in PSA levels was noticed after 6 months, whereafter over the following 24 months there was no significant further increase (85). Other studies have found a rise of PSA levels after 3 months (40), some only after 12 months (43).

This medication may also reduce liver function and can cause liver failure. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles.

If reducing the frequency of injections is important to you, Testosterone Cypionate might be a slightly more convenient option—but it’s not a make-or-break factor for most. These changes can significantly impact quality of life, prompting many men to explore treatment options (Saad et al., 2017). Testosterone is a controlled substance regulated by the United States government and must only be taken when prescribed. However, taking some precautionary measures before initiating the therapy is best. Treatments could last for a lifetime or be short term, depending on the individual’s circumstances.